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221 Main - Restaurant & Cocktail House

About Us

Welcome to 221 Main - Restaurant & Cocktail House an award-winning steakhouse in the heart of St. Joseph, MI. Since 2012, we have been delighting diners with our delicious steaks, seafood dishes, burgers, and an extensive selection of wines, craft cocktails, and draft beers. Beyond our exceptional menu, we also offer event space rentals, catering services, private dining options, and convenient takeout for those craving our delectable dishes at home. Come experience the perfect blend of culinary excellence and warm hospitality at 221 Main - where every meal is an unforgettable experience. Stop by today!

Our Story

Welcome to 221 Main - Restaurant & Cocktail House, an award-winning steakhouse nestled in the vibrant heart of St. Joseph, Michigan. Since our establishment in 2012, we have been dedicated to providing an unforgettable dining experience, showcasing a culinary journey that satisfies a diverse range of palates. Our menu is a celebration of flavor, featuring a variety of dishes crafted from the finest ingredients.

At 221 Main, we take pride in our steaks. For steak lovers, our offerings include classic cuts like the ribeye and filet mignon, available daily to ensure that every visit can be a special occasion. But we don’t stop there; we have signature dishes like our indulgent Surf-n-Turf and the uniquely seasoned BC Ribeye, which are sure to tantalize your taste buds. Our commitment to quality and flavor is reflected in every bite, making our steaks not just meals, but memorable experiences.

Seafood enthusiasts will also find plenty to love on our menu. Our Atlantic Salmon and Perch are freshly prepared, capturing the essence of coastal cuisine. Other standout dishes include the savory Chicken Marsala, creamy Mac & Cheese, and our delightful Seafood Pasta—each carefully crafted to ensure a delightful dining experience. Whether you’re stopping by for a casual dinner or celebrating a special occasion, 221 Main is the perfect destination.

In addition to our exceptional food, we boast a vibrant bar scene. Our hand-crafted cocktails are a highlight, expertly mixed to elevate your dining experience. Pair your meal with one of our select craft beers, featuring local brews and popular favorites. Wine lovers will appreciate our curated wine list, showcasing an array of choices from local wineries and esteemed vineyards from around the globe. We strive to offer something for every palate, ensuring that every sip enhances your meal.

221 Main is not just a restaurant; it’s also a versatile venue for events. We offer event space rentals, making us an ideal choice for gatherings of all sizes, from intimate celebrations to corporate functions. Our catering services bring the culinary excellence of our kitchen to your events, while our private dining options provide a personalized touch for those special occasions. For those craving our delectable dishes at home, we offer convenient takeout services, allowing you to enjoy the 221 Main experience wherever you are.

What truly sets 221 Main apart is our unwavering commitment to hospitality. From the moment you walk through our doors, you’ll be greeted with warmth and attentiveness, ensuring that every visit feels special. Our dedicated staff works diligently to provide exceptional service, making it their mission to exceed your expectations.
Join us at 221 Main - Restaurant & Cocktail House, where culinary excellence meets warm hospitality. Whether you’re a regular or a first-time visitor, we invite you to indulge in an array of flavors and create lasting memories with us. Stop by today and discover why we’ve become a beloved dining destination in St. Joseph!

Areas Served

Berrien County, MI | Cass County, MI | Van Buren County, MI | Allegan County, MI | Kalamazoo County, MI | Kent County, MI | Lake County, IN | St. Joseph, MI | St. Joseph County, IN

What We Offer

Our Specialties include:

Our Services include:

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Testimonials

On 11/19/2024 Karen T had this to say:
Great atomosphere, delicious food! Had the BC Ribeye and brussel sprouts - amazing. Special shout out to our amazing server Crystal - she’s the best! Efficient and friendly - can’t wait to come back!

On 11/18/2024 Karen Thier had this to say:
Great atmosphere, delicious food! Had the BC Ribeye which was amazing - Brussel sprout appetizer wonderful. Special shout out to our amazing server Crystal - efficient and friendly She’s the best! Can’t wait to come back!

On 10/29/2024 brian winger had this to say:
Awesome restaurant!

On 10/20/2024 Jay Hön had this to say:
Our first time here and we had the short ribs & garlic ribeye. Both were absolutely delicious. Asparagus with hollandaise sauce was very good as well. Sadly, we had the last creme brulee, and it wasn't gelled together very well. This was my reason for picking this restaurant. Otherwise, 5 stars across the board. Waitress was wonderful as well. A++ for calling out everything on the menu that is Gluten-free!!! It made selecting this restaurant SUPER EASY!

On 10/5/2024 Britni Shindeldecker had this to say:
We came here for a celebratory dinner, party of 4. The food was phenomenal, started off with firecracker shrimp, and calamari. For the main meals we had two surf and turf meals, garlic ribeye meal, and regular ribeye meal and everything was absolutely perfect. Our waitress was very kind, on top of refills, and checking to see if we needed anything. We came in right as they were opening around 5. Highly recommend. Hats off to the chef for an amazing meal.

Contact Us

221 Main - Restaurant & Cocktail House
221 Main St St joseph, MI 49085
Phone: (269) 982-4000
Email: 221reservations@gmail.com

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Payment Types Accepted

American Express, Android Pay, Apple Pay, Cash, Debit Cards, Discover, MasterCard, Visa

Our Hours

Holiday Hours May Vary. Please Call For Details.

Thursday: 5:00 PM - 9:00 PM Copper Pot Breakfast Hours: 8 am - 12 pm
Friday: 5:00 PM - 9:00 PM Copper Pot Breakfast Hours: 8 am - 12 pm
Saturday: 5:00 PM - 9:00 PM Copper Pot Breakfast Hours: 8 am - 1 pm
Sunday: 5:00 PM - 9:00 PM Copper Pot Breakfast Hours: 8 am - 2 pm

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